Chronic Kidney Disease: A single day screening on World Kidney Day for five consecutive years

Main Article Content

Rai Pradeep K*
Rai Punam
Bedi Sonam

Abstract

Introduction: Chronic kidney disease is a costly and burdensome public health concern. Delayed recognition and treatment of CKD may predispose patients to unfavorable future outcomes and burden the healthcare services. The early detection of disease via screening programs is widely recommended. The present study is a hospital camp-based screening for detecting patients with chronic kidney disease in Varanasi from 2014-18.


Methods: The study subjects constituted 436 apparently healthy adults (age ≥18 years) of Varanasi. Information on socio-demographic profile, personal characteristics and clinical investigations were recorded. Stepwise binary logistic regression analysis was applied to find the significant predictors of chronic kidney disease.


Results: Median age of the study subjects was 40.5 years. There were 39.7% males and 60.3% females. Chronic kidney disease was found in 23.9% subjects. Underweight, diabetes mellitus, hypertension, smoking status and higher creatinine levels came out as significant predictors of chronic kidney disease.


Conclusion: We screened apparently healthy individuals and found very high percentages of chronic kidney disease and its predictors. Henceforth, understanding the preventable and modifiable risk factors of chronic kidney disease becomes a prerequisite to intervene before risk populations reaches to irreversible stages of adverse future outcomes.

Article Details

K, R. P., Punam, R., & Sonam, B. (2019). Chronic Kidney Disease: A single day screening on World Kidney Day for five consecutive years. Journal of Clinical Nephrology, 3(1), 046–054. https://doi.org/10.29328/journal.jcn.1001025
Research Articles

Copyright (c) 2019 Rai PK, et al.

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Everett B, Castel LD, McGinnis M, Beresky A, Cane RC Jr, et al. Economic and Clinical Outcomes Resulting From the Stage 4 Chronic Kidney Disease Case Management Quality Improvement Initiative. Prof Case Manag. 2017; 22: 291. Ref.: https://goo.gl/joWb7W

Ojo A. Addressing the Global Burden of Chronic Kidney Disease through Clinical and Translational Research. Trans Am Clin Climatol Assoc. 2014; 125: 229-243. Ref.: https://goo.gl/6DzNKh

Mendelssohn DC. Coping with the CKD Epidemic: The Promise of Multidisciplinary Team-Based Care. Nephrol Dial Transplant. 2005; 20: 10–12. Ref.: https://goo.gl/W3r8bm

Levey AS, Bosch JP, Lewis JB, Greene T, Rogers N, et al. A More Accurate Method to Estimate Glomerular Filtration Rate from Serum Creatinine: A New Prediction Equation. Ann Intern Med. 1999; 130: 461–70. Ref.: https://goo.gl/MdkXrh

Ulasi II, Ijoma CK, Onodugo OD, Arodiwe EB, Ifebunandu NA, et al. 2013. Towards Prevention of Chronic Kidney Disease in Nigeria: A Community-Based Study in Southeast Nigeria. Kidney International Supplements. 2017; 3: 195–201. Ref.: https://goo.gl/CRpz9b

Ketteler M, Block GA, Evenepoel P, Fukagawa M, Herzog CA, et al. Executive Summary of the 2017 KDIGO Chronic Kidney Disease–Mineral and Bone Disorder (CKD-MBD) Guideline Update: What’s Changed and Why It Matters. Kidney Int. 2017; 92: 26–36. Ref.: https://goo.gl/RfKNHH

Neuen BL, Chadban SJ, Demaio AR, Johnson DW, Perkovic V. Chronic Kidney Disease and the Global NCDs Agenda. BMJ Glob Health. 2017; 2: e000380. Ref.: https://goo.gl/z3ZfYW

Wang H, Naghavi M, Allen C, Barber RM, Bhutta ZA, et al. Global, Regional, and National Life Expectancy, All-Cause Mortality, and Cause-Specific Mortality for 249 Causes of Death, 1980–2015: A Systematic Analysis for the Global Burden of Disease Study 2015. The Lancet. 2016; 388: 1459–1544. Ref.: https://goo.gl/86Yu6C

Agarwal SK, Dash SC, Irshad M, Raju S, Singh R, et al. Prevalence of Chronic Renal Failure in Adults in Delhi, India. Nephrol Dial Transplant. 2005; 20: 1638–1642. Ref.: https://goo.gl/zkKD9D

Haroun MK, Jaar BG, Hoffman SC, Comstock GW, Klag MJ, et al. Risk Factors for Chronic Kidney Disease: A Prospective Study of 23,534 Men and Women in Washington County, Maryland. J Am Soc Nephrol. 2003; 14: 2934–2941. Ref.: https://goo.gl/hc9Qbd

Ležaić V, Bajčetić S, Peruničić-Peković G, Bukvić D, Dimković N, et al. Screening of Elderly for Chronic Kidney Disease. Kidney Blood Press Res. 2012; 35: 497–503. Ref.: https://goo.gl/FqrKTX

Modi GKVM, Jha V. The Incidence of End-Stage Renal Disease in India: A Population-Based Study. Kidney int. 2006; 70: 2131–2133. Ref.: https://goo.gl/bMGC4K

Rai PK, Rai P, Bedi S. Prevalence and Risk Factors of Chronic Kidney Disease: A Single Day Screening on World Kidney Day for Four Consecutive Years in Varanasi. Urology & Nephrology Open Access Journal. 2018; 6: 167–171. Ref.: https://goo.gl/3TqPQe

Rai PK, Jindal PK, Rai P, Rai PK, Rai SN, et al. Screening of Chronic Kidney Disease (CKD) in General Population on World Kidney Day on Three Consecutive Years: A Single Day Data. Int J Med Public health. 2014; 4: 167-170. Ref.: https://goo.gl/8ixfzs

Singh AK, Farag YM, Mittal BV, Subramanian KK, Reddy SR, et al. Epidemiology and Risk Factors of Chronic Kidney Disease in India–results from the SEEK (Screening and Early Evaluation of Kidney Disease) Study. BMC nephrology. 2013; 14: 114. Ref.: https://goo.gl/Q3WhJ4

Hill NR, Fatoba ST, Oke JL, Hirst JA, O'Callaghan CA, et al. Global Prevalence of Chronic Kidney Disease–a Systematic Review and Meta-Analysis. PloS One. 2016; 11: e0158765. Ref.: https://goo.gl/7ph4Jy

Varma PP. Prevalence of Chronic Kidney Disease in India-Where Are We Heading? Indian J Nephrol. 2015; 25: 133-135. Ref.: https://goo.gl/fwdfDs

Levey AS, Eckardt KU, Tsukamoto Y, Levin A, Coresh J, et al. Definition and Classification of Chronic Kidney Disease: A Position Statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 2005; 67: 2089–2100. Ref.: https://goo.gl/HEvXdc

Sherwood M, McCullough PA. Chronic Kidney Disease from Screening, Detection, and Awareness, to Prevention. Lancet Glob Health. 2016; 4: e288–289. Ref.: https://goo.gl/tr7TU2

WebsterAC, Nagler EV, Morton RL, Masson P. Chronic Kidney Disease. The Lancet. 2017; 389(10075): 1238–1252. Ref.: https://goo.gl/b8225L

KazancioğluR. Risk Factors for Chronic Kidney Disease: An Update. Kidney Int Suppl. 2013; 3: 368–371. Ref.: https://goo.gl/2dMuVf

Yacoub R, Habib H, Lahdo A, Al Ali R, Varjabedian L, et al. Association between Smoking and Chronic Kidney Disease: A Case Control Study. BMC Public Health. 2010; 10: 731. Ref.: https://goo.gl/Ca8KPU

Orth SR. Smoking and the Kidney. JASN. 2002; 13: 1663–1672. Ref.: https://goo.gl/bDTt93

Baumgarten M, Gehr T. Chronic Kidney Disease: Detection and Evaluation. American Family Physician. 2011; 84: 1138-1148. Ref.: https://goo.gl/BgUr8M

Woodhouse S, Batten W, Hendrick H, Malek PA. The Glomerular Filtration Rate: An Important Test for Diagnosis, Staging, and Treatment of Chronic Kidney Disease. Laboratory Medicine. 2015; 37: 244–246. Ref.: https://goo.gl/38aakC

Coresh J, Astor BC, Greene T, Eknoyan G, Levey AS. Prevalence of Chronic Kidney Disease and Decreased Kidney Function in the Adult US Population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis. 2003; 41: 1–12. Ref.: https://goo.gl/nJ5a4K

Lindeman RD, Tobin J, Shock NW. Longitudinal Studies on the Rate of Decline in Renal Function with Age. J Am Geriatr Soc. 1985; 33: 278–285. Ref.: https://goo.gl/nyo1nN

Turin TC, James M, Ravani P, Tonelli M, Manns BJ, et al. Proteinuria and Rate of Change in Kidney Function in a Community-Based Population. J Am Soc Nephrol. 2013; 24: 1661-1667. Ref.: https://goo.gl/SKBQ1B

Pounds LL, Teodorescu VJ. Chronic Kidney Disease and Dialysis Access in Women. J Vasc Surg. 2013; 57: 49S–53S. Ref.: https://goo.gl/uQX5nw

Kovesdy CP, Anderson JE, Kalantar-Zadeh K. Paradoxical Association between Body Mass Index and Mortality in Men with CKD Not yet on Dialysis. Am J Kidney Dis. 2007; 49: 581–591. Ref.: https://goo.gl/VJs2he

Fouad M, Ismail MI, Gaballah A, E Reyad, ELdeeb S. Prevalence of Obesity and Risk of Chronic Kidney Disease among Young Adults in Egypt. Indian J Nephrol. 2016; 26: 413-418. Ref.: https://goo.gl/tbWnHM

Kovesdy CP, Furth SL, Zoccali C, World Kidney Day Steering Committee. Obesity and Kidney Disease: Hidden Consequences of the Epidemic. Nephron. 2017; 135: 243–251. Ref.: https://goo.gl/EZUuUf

Mallamaci F, Tripepi G. Obesity and CKD Progression: Hard Facts on Fat CKD Patients. Nephrol Dial Transplant. 28(suppl_4): iv105-iv108. Ref.: https://goo.gl/xZoANq

Blüher M. Are There Still Healthy Obese Patients? Current Opinion in Endocrinology. Diabetes and Obesity. 2012; 19: 341–346. Ref.: https://goo.gl/ckbz1z

Lopez-Giacoman S, Madero M. Biomarkers in Chronic Kidney Disease, from Kidney Function to Kidney Damage. World J Nephrol. 2015; 4: 57-73. Ref.: https://goo.gl/8z183s

Abcar AC, Chan L, Yeoh H. What To Do for the Patient with Minimally Elevated Creatinine Level? Perm J. 2004; 8: 51-53. Ref.: https://goo.gl/1CE9v3

Lin CC, Li CI, Liu CS, Lin WY, Lin CH, et al. Development and Validation of a Risk Prediction Model for End-Stage Renal Disease in Patients with Type 2 Diabetes. Sci Rep. 2017; 7: 10177. Ref.: https://goo.gl/MxtHcN

Veerappan I, Abraham G. Chronic Kidney Disease: Current Status, Challenges and Management in India. Ch. 2013; 130: 593–597. Ref.: https://goo.gl/D763yt

Weiner DE, Tighiouart H, Amin MG, Stark PC, MacLeod B, et al. Chronic Kidney Disease as a Risk Factor for Cardiovascular Disease and All-Cause Mortality: A Pooled Analysis of Community-Based Studies. J Am Soc Nephrol. 2004; 15: 1307–1315. Ref.: https://goo.gl/KkEj5z