Figure 8

Collecting duct PGE2 responses reduce water loss with empagliflozin in mice with type 2 diabetes mellitus

R Nasrallah, J Zimpelmann, V Cheff, JF Thibodeau, KD Burns and RL Hébert*

Published: 08 April, 2021 | Volume 5 - Issue 1 | Pages: 023-030

jcn-aid1069-g008

Figure 8:

Renal V2R and UTA1 gene expression. RNA was isolated from microdissected cortical (A+B) and inner medullary (C) collecting ducts from 4 mouse groups: control (db/m), db/m+EMPA, diabetic db/db, and db/db+EMPA. Expression of vasopressin V2 receptors (V2R) and urea transporterA1 (UTA1) mRNA were measured by qPCR. Data was normalized to 18S and is presented as fold db/m of mean +/- SEM. * p < 0.05 vs. db/m, n = 5-6.

Read Full Article HTML DOI: 10.29328/journal.jcn.1001069 Cite this Article Read Full Article PDF

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