Abstract

Research Article

Doppler Evaluation of Renal Vessels in Pediatric Patients with Relapse and Remission in Different Categories of Nephrotic Syndrome

Amit Nandan Dhar Dwivedi*, Srishti Sharma, OP Mishra and Girish Singh

Published: 29 September, 2023 | Volume 7 - Issue 3 | Pages: 067-072

Aim: To study resistivity & pulsatility indices in the interlobar arteries of kidneys in patients with idiopathic nephrotic syndrome and evaluate their response to steroids 
Method: The prospective case-control study was carried out in 100 patients, aged 2 years - 15 years of nephrotic syndrome and divided into 5 groups depending upon their response to steroids. Twenty-five age-matched controls were included for comparison. The abdominal ultrasonography and Doppler examinations were performed for patients of each group and for the controls. 
Result: The mean Resistivity Index (RI) and Pulsatility Index (PI) of the interlobar arteries were calculated for the five subgroups of nephrotic syndrome patients and for the controls. There was a significant difference in mean RI in all the evaluated arteries between the 6 groups. No significant difference was noted in the pulsatality indices of the kidney of the cases of nephrotic syndrome when compared to controls. 
Conclusion: Steroid-resistant nephrotic syndrome patients show a statistically significant difference in RI and not a statistically significant difference in PI Doppler parameters when groups of patients compared to controls. These parameters may be used to predict the response to steroids. 

Read Full Article HTML DOI: 10.29328/journal.jcn.1001112 Cite this Article Read Full Article PDF

Keywords:

Nephrotic syndrome; Resistive index; Pulsatality index; Ultrasonography

References

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