Liver cyst infection in kidney transplant patient with autosomal dominant polycystic kidney disease: Interest of PET/CT in diagnosis and treatment

Main Article Content

Georgery H*
Migali G
Pochet JM
Tintillier M
Van Ende C
Cuvelier C

Abstract

Liver cyst infection in patients with autosomal dominant polycystic kidney disease (ADPKD) is a rare but life-threatening complication. Diagnosis and treatment remain challenging. We report the case of a 64-year-old kidney transplant patient presenting with fever and abdominal pain. The diagnosis of liver cyst infection was made by positron emission tomography scan (PET/CT). Moreover, the course of our patient illustrates the interest of subsequent PET/CT during follow-up as our patient failed on antibiotherapy and required liver cyst drainage.

Article Details

H, G., G, M., JM, P., M, T., C, V. E., & C, C. (2018). Liver cyst infection in kidney transplant patient with autosomal dominant polycystic kidney disease: Interest of PET/CT in diagnosis and treatment. Journal of Clinical Nephrology, 2(3), 053–056. https://doi.org/10.29328/journal.jcn.1001019
Case Reports

Copyright (c) 2018 Georgery H, et al.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Gall TM, Oniscu GC, Madhavan K, Parks RW, Garden OJ. Surgical management and longterm follow‐up of non‐parasitic hepatic cysts. HBP (Oxford). 2009; 11: 235-241. Ref.: https://goo.gl/nXsEUK

Pirson Y, Kanaan N. Complications infectieuses associées à la polykystose rénale autosomique dominante. Nephrol ther. 2015; 11: 73-77. Ref.: https://goo.gl/7XVxEt

Lantinga MA, Geudens A, Gevers TJG, Drenth JPH. Systematic review: the management of hepatic cyst infection. Aliment Pharmacol Ther. 2015; 41: 253–261. Ref.: https://goo.gl/B33yyd

Sallee M, Rafat C, Zahar JR, Paulmier B, Grunfeld JP, et al. Cyst infections in patients with Autosomal Dominant Polycystic Kidney Disease. Clin J Am Soc Nephrol. 2009; 4: 1183-1189. Ref.: https://goo.gl/UKhJVJ

Lantinga MA, De Sevaux RG, Drenth JP. 18F-FDG PET/CT during diagnosis and followup of recurrent hepatic cyst infection in autosomal dominant polycystic kidney disease. Clin Nephrol. 2015; 84: 61–64. Ref.: https://goo.gl/4JUrij

Neuville M, Hustinx R, Jacques J, Krzesinski JM, Jouret F. Diagnostic Algorithm in the Management of Acute Febrile Abdomen in Patients with Autosomal Dominant Polycystic Kidney Disease. PLoS ONE. 2016; 11: e0161277. Ref.: https://goo.gl/zbGgUP

Fukasawa H, Kaneko M, Niwa H, Yasuda H, Kumagai H, et al. Carbohydrate antigen 19-9 is significantly elevated in autosomal dominant polycystic kidney disease. Nephrology (Carlton). 2018; 23: 210-216. Ref.: https://goo.gl/awzFJ6

Lantiga MA, Drenth JP, Gevers TJ. Diagnostic criteria in renal and hepatic cyst infection. Nephrology Dialysis Transplantation. 2015; 30: 744-7451. Ref.: https://goo.gl/p5Qjj4

Chapman AB, Devuyst O, Eckardt KU, Gansevoort RT, Harris T, et al. Autosomal Dominant Polycystic Kidney Disease (ADPKD): Executive Summary from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney international. 2015; 88: 17-27. Ref.: https://goo.gl/RtcfYY

Suwabe T, Araoka H, Ubara Y, Kikuchi K, Hazue R, et al. Cyst infection in autosomal dominant polycystic kidney disease: causative microorganisms and susceptibility to lipidsoluble antibiotics. Eur J Clin Microbiol Infect Dis. 2015; 34: 1369–1379. Ref.: https://goo.gl/yd4XSB

Pirson Y, Chauveau D, Devuyst O. Autosomal dominant polycystic kidney disease. In: Davidson AM, editor. Oxford textbook of clinical nephrology. 3rd ed, Oxford: Oxford University Press. 2005; 2304-24.