Complete recovery of chronic Osmotic Demyelination Syndrome with plasma exchange

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Submitted: February 19, 2018
Published: Mar 8, 2018
DOI: 10.29328/journal.jcn.1001011
Keywords:
Hyponatremia, Osmotic demyelination syndrome, Plasma exchange
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Sumbal Nasir Mahmood*
Professor and Head of Nephrology Department at Ziauddin Hospital, Karachi, Pakistan
Kunwer Naveed Mukhtar
Professor and Head of Nephrology at Liaquat National Hospital, Pakistan
Osama Kunwer Naveed
Medical Student at Dow University of Health Sciences, Karachi, Pakistan
Ahmed Kunwer Naveed
Student at Dow University of Health Sciences, Karachi, Pakistan

Abstract

A 50-years old female presented with dysarthria, inability to swallow and quadriparesis for three weeks. She had rapid correction of her serum sodium (Na) from 99meq/l to 138meq/l within 24 hours 1 week prior to development of these symptoms. She was diagnosed as a case of Osmotic demyelination syndrome (ODS) formerly known as central pontine myelinolysis (CPM) which was confirmed by MRI. She underwent Plasma Exchange (PE) on the 20th day since her symptoms started and underwent 7 cycles of PE with complete neurological recovery. Pt was discharged with ability to ambulate independently and complete recovery of speech and swallowing. Hence, we report that PE is beneficial in chronic ODS.

Article Details

Mahmood, S. N., Mukhtar, K. N., Naveed, O. K., & Naveed, A. K. (2018). Complete recovery of chronic Osmotic Demyelination Syndrome with plasma exchange. Journal of Clinical Nephrology, 2(1), 005–007. https://doi.org/10.29328/journal.jcn.1001011
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Copyright (c) 2018 Mahmood SN, et al.

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This work is licensed under a Creative Commons Attribution 4.0 International License.

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