Case Report

Complete recovery of chronic Osmotic Demyelination Syndrome with plasma exchange

Sumbal Nasir Mahmood*, Kunwer Naveed Mukhtar, Osama Kunwer Naveed and Ahmed Kunwer Naveed

Published: 08 March, 2018 | Volume 2 - Issue 1 | Pages: 005-007

A 50-years old female presented with dysarthria, inability to swallow and quadriparesis for three weeks. She had rapid correction of her serum sodium (Na) from 99meq/l to 138meq/l within 24 hours 1 week prior to development of these symptoms. She was diagnosed as a case of Osmotic demyelination syndrome (ODS) formerly known as central pontine myelinolysis (CPM) which was confirmed by MRI. She underwent Plasma Exchange (PE) on the 20th day since her symptoms started and underwent 7 cycles of PE with complete neurological recovery. Pt was discharged with ability to ambulate independently and complete recovery of speech and swallowing. Hence, we report that PE is beneficial in chronic ODS.

Read Full Article HTML DOI: 10.29328/journal.jcn.1001011 Cite this Article Read Full Article PDF


Hyponatremia; Osmotic demyelination syndrome; Plasma exchange


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